TENSIN相关论文
10号染色体上与张力蛋白同源的酪氨酸磷酸酶基因(phosphatase and tensin homolog deleted on chromosome ten,PTEN)是一个新发现......
Effects of valsartan on matrix metalloproteinase-2 and tissue inhibitor of matrix metalloproteinase-
Background To observe the effects of valsartan on matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix meta......
该研究旨在检验可诱导型血管紧张素Ⅱ(angio-tensinⅡ,AngⅡ)依赖性恶性高血压转基因大鼠模型[TGR(Cyp1a1Ren2)]肾内的肾素血管紧......
《中国高血压防治指南2010》(《指南》)已正式发表,新版指南大幅拓宽了肾素血管紧张素醛固酮系统(renin angiotensin aldosterone ......
目的 研究罗格列酮对低氧性肺动脉高压大鼠过氧化物酶体增殖物激活受体γ和10号染色体缺失张力蛋白同源磷酸酶基因表达的影响。方......
目的研究人第10号染色体缺失的磷酸酶及张力蛋白同源基因(phosphatase and tensin homolog deleted on chromosome 10,PTEN)在小鼠......
对乳腺癌抑癌基因的研究 ,有助于推动乳腺癌病因、发生、发展及预后的研究 ,从而使乳腺癌的发病机理更加明确。现将近几年乳腺癌几......
Rapid construction of phosphatase and tensin homolog-deleted on chromosome ten gene recombinant aden
Recent studies have shown that phosphatase and tensin homolog-deleted on chromosome ten(PTEN) gene plays an important ro......
Ischemic postconditioning enhances glycogen synthase kinase-3β expression and alleviates cerebral is
The present study established global brain ischemia using the four-vessel occlusion method.Following three rounds of rep......
This study describes a detailed process for obtaining brain glioma stem cells from freshly dissected human brain glioma ......
肿瘤的发生、发展必有癌基因的激活与抑癌基因的失活.1997年,研究人员从10q23.3染色体上克隆到了PTEN基因(磷酸酶张力蛋白基因,pho......
给清醒狗注射灵杆菌内毒素,观察血清和肺组织匀浆血管紧张素转化酶(ACE)活性的变化。发现注射内毒素后血清ACE活性明显升高,肺组织......
phosphatase and tensin homolog is a differential diagnostic marker between nonalcoholic and alcoholi
AIM: To investigate the protein expression of phosphatase and tensin homolog(PTEN) in human liver biopsies of patients w......
Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma c
阜阳市局 ￡4a 局长——_MINtkMMtgj’＃lnH＄B——q.M——D收束志不他只邀狲位J则【科校为先导推动地租工作.B为广为戳民U用凶盼引眯B.......
AIM:To investigate in vitro effects and mechanisms of silibinin on hepatocellular carcinoma(HCC)cell growth. METHODS:Hum......
PTEN是迄今发现的第一个具有双重特异性磷酸酶活性的肿瘤抑制基因,在细胞的生长发育、凋亡、迁移、信号传递等方面起着重要的调控......
Inhibitory effect of tea polyphenals on transforming growth factor-β1 expression in rat with cyclosp
AIM: To investigate the inhibitory effect of tea polyphenols (TP)on the transforming growth factor-pi (TGF-β1) expressi......
本文叙述了当前国内外抑癌基因PTEN(phosphatase and tensin homology deleted on chromosome ten,PTEN)在胶质瘤细胞中的信号传导......
The phosphoinositide 3-kinase (PI3K)/phosphatase and tensin homolog (PTEN)/Akt axis is a key signal transduction node th......
Cowden syndrome is a rare autosomal dominant disorder that is characterized by multiple hamartomas in a variety of tissu......
PTEN / MMAC1/ TEP1基因是目前发现的第一个具有磷酸酶活性的抑癌基因。PTEN基因位于染色体10 q2 3区 ,与多种散发性肿瘤和几种家......
AIM: To investigate the tumor-suppressive effect of the phosphatase and tensin homologue deleted from chromosome (PTEN) ......
Effects of angiotensin converting enzyme inhibitor,angio-tensin II type I receptor blocker and their
Background Transforming growth factor (TGF) β1-Smads signal plays an important role in cardiac remodeling following myo......
本文设计、合成了一系列咳嗽衍生物（Ⅰ－Ⅱ），并检测了它们的血管紧张素Ⅱ受体拮机活性。以ZD-731（pA2＝84）为先导化合物，用生物电子等排的N－苯......
miRNA作为内源性非编码小RNA,主要在转录后水平调控基因表达。近年来越来越多的证据表明,miRNA通过调控脂肪细胞分化相关的转录因......
目的研究10号染色体缺失磷酸酶及张力蛋白同源体(Phosphatase and tensin homolog deleted on chromosome ten,PTEN)再表达对细胞......
目的:研究骨形成蛋白-2(BMP-2)对低氧状态下人肺动脉平滑肌细胞(Pu lmonary artery smooth musc le cells,PASMCs)的PTEN(Phosohat......
Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cel
AIM:To investigate the impact of phosphatase and tensin homolog(Pten) in the specification of intestinal enteroendocrine......
All-trans retinoic acid inhibited angiotensin Ⅱ-induced increase in cell growth and collagen secreti
Aim:To determine whether all-trans retinoic acid(atRA)acts to modulate angio-tensin Ⅱ(Ang Ⅱ)-induced cardiac fibrobla......
目的:研究新疆阿魏乙酸乙酯提取物对人结肠腺癌Caco-2细胞迁移、侵袭的影响,并探讨其相关机制。方法:以Caco-2细胞为研究对象,用6.......
有人提出把肾素血管紧张素系统(renin-angio-tensin system,RAS)阻断剂放入饮用水中以防止肾病的发生发展,降低心血管风险,并可通......
Expression of phosphatase and tensin homolog deleted on chromosome ten in liver of athymic mice with
AIM: To explore the expression of phosphatase and tensin homolog deleted on chromosome ten (PTEN) in liver of athymic mi......
Hepatocellular carcinoma(HCC)is one of the leading causes of cancer-related death in the world.The carcinogenesis of HCC......
AIM: To investigate the association between single nucleotide polymorphisms (SNPs) in the phosphatase and tensin homolog......
PTEN基因的突变失活在子宫内膜癌的发生、发展中起重要的作用。全文综述其在子宫内膜癌组织中的研究与应用。
PTEN gene mutation......
Objective:The aim of our study was to explore the correlations between both the genes,evolution and prognosis of the dis......
MicroRNAs (miRNAs) are 21 to 24 nucleotide,non-coding RNA molecules that post-transcriptionally regulate the expression ......
SMAD-4在肿瘤抑制方面有重要作用,但它在肿瘤发生中的作用及其与细胞周期进程中的一种关键调控因子——PTEN(phosphatase and tens......
AIM:To determine the functional significance of TC21 in esophageal squamous cell carcinoma(ESCC).METHODS:TC21 siRNA tran......
Phosphatase and tensin homolog expression related to cetuximab effects in colorectal cancer patients
AIM: To investigate the correlation between expression of phosphatase and tensin homolog (PTEN) and cetuximab effects in......
The expression of phosphatase and tensin homolog (PTEN ), a tumor suppressor gene, is frequently downregulated in gastri......
AIM:To investigate the effects of small interference RNA(siRNA) targeting of Cdx2 on human gastric cancer MGC-803 cells ......
目的:探讨PTEN(phosphatase and tensin homologue deleted on chromosometen)和磷酸化AKT(phosphorylated-AKT,p-AKT)蛋白在胃癌......
抑癌基因磷酸酶与张力蛋白同源物(phosphatase and tensin homolog,PTEN)基因的功能缺失往往会形成多种类型的癌症,它的表达在转录......
PTEN and Ki67 expression is associated with clinicopathologic features of non-small cell lung cancer
Phosphatase and tensin homolog deleted on chromosome 10(PTEN) and the proliferating antigen Ki67 have been widely studie......
AIM: To investigate the effect of metformin on silibinin-induced apoptosis in human colorectal cancer(COLO 205) cells.ME......
目的:构建抑癌基因PTEN(phosphatase and tensin homolog deleted on chromosome ten)的转基因小鼠模型并对其表型进行初步分析。......
