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Design, synthesis and the mechanism of anti-atherosclerosis of The novel Tetramethylpyrazine derivat
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目的 探讨川芎嗪的抗抑郁作用.方法 采用强迫游泳实验制备急性应激大鼠抑郁模型,长期轻度应激+孤养制备大鼠慢性抑郁模型.慢性应激......
建立了用气相色谱-质谱检测法同时测定血浆中冰片和川芎嗪血药浓度的方法。冰片和川芎浓度在10-300ng/ml范围内线性关系良好,冰片和川芎嗪的血中......