diseasemodel相关论文
由于神经保护药的临床研究均以失败告终,因此卒中治疗专业委员会建议利用非人灵长类动物开展卒中临床前研究。非人灵长类动物是基础......
Mitochondrial diseases are clinical phenotypes associated with mitochondrial dysfunction, which can be caused by mutatio......
Echocardiographic Evaluation of Coronary Abnormalities and Cardiac Function in a Murine Model of Kaw
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Efficient Generation of Gene-Modified Pigs Harboring Precise Orthologous Human Mutation via CRISPRCa
Precise generic mutation of model animals is highly valuable for functional investigation of human mutations.Cluster......
Efficient Generation of Gene-Modified Pigs HarboringPrecise Orthologous Human Mutation via CRISPRCas
Precise genetic mutation of model animals is highly valuable for functional investigation of human mutations.Cluster......
BACKGROUND: The pathological mechanism of secondary brain lesion following an embolism remains unclear. The establishmen......
目的采用兔耳缘静脉注射肾上腺素的方法建立中心性浆液性脉络膜视网膜病变(CSC)动物模型,为CSC发病机制和防治研究提供动物模型。方......
氧诱导视网膜病变(OIR)模型已在猫、小鼠、大鼠、家兔、犬和斑马鱼等动物上建立,对视网膜新生血管发生机制和治疗的研究起到了重要......
Cre/LoxP系统在新型基因打靶中应用广泛,可对特定组织和器官中的基因进行改造,将特定的基因片段删除,以研究特定基因对生长发育的......
Sepsis can cause a series of damages to various organs of the body, so it has always been regarded as a hot research top......
目的:建立新生BALB/c小鼠巨细胞病毒肝炎模型。方法:小鼠巨细胞病毒经腹腔注射感染新生BALB/c小鼠,建立肝炎小鼠模型。结果:感染小......
目的显微镜下建立一种能很好模拟人体内生物学行为的胃癌裸小鼠原位移植和转移模型.方法采用人胃癌SGC-7901细胞株在裸鼠皮下反复......
AIM: To study the role of hybrid bioartificial liver (HBL) in clearing proinflammatory cytokines and endotoxin in patien......
目的 通过观察山东、河南、四川3个道地产区丹参混合提取物对大鼠局灶性脑缺血再灌注后脑组织B细胞淋巴瘤-2基因(Bc1-2)、肿瘤抑制......
Although CRISPR/Cas9-mediated gene editing is widely applied to mimic human disorders,whether acute manipulation of dise......
Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaq
Retinitis pigmentosa (RP) is a form of inherited retinal degenerative diseases that ultimately involves the macula,which......