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5. Activity of the c-Met inhibitor tepotinib (MSC2156119J) in combination with gefitinib in Asian patie

Activity of the c-Met inhibitor tepotinib (MSC2156119J) in combination with gefitinib in Asian patie

来源 :第十八届全国临床肿瘤学大会暨2015年CSCO学术年会 | 被引量 : 0次 | 上传用户：zangming

【摘 要】

：

　　Objective: c-Met abnormalities can cause resistance to EGFR TKIs in EGFR mutant NSCLC patients (pts).The highly selective c-Met inhibitor tepotinib (MSC2156

【作 者】

：

Yi-long Wu Keunchil Park Dong-wan Kim Ross a.Soo Huiling Xiong Cindy Li Christian Ihling James chih-hsin Yang 

【机 构】

：

Lung Cancer, Guangdong General Hospital (GGH) & Guangdong Academy of Medical Sciences, Guangzhou, Ch

【出 处】

：

第十八届全国临床肿瘤学大会暨2015年CSCO学术年会

【发表日期】

：

2015年期

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　　Objective: c-Met abnormalities can cause resistance to EGFR TKIs in EGFR mutant NSCLC patients (pts).The highly selective c-Met inhibitor tepotinib (MSC2156119J) had promising activity in a phase Ⅰ trial in pts with advanced solid tumors.

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