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Poly(N-isopropylacrylamide) (PNIPAM) is a typical thermoresponsive polymer,and it exhibits a lower critical solution temperature (LCST) at 32 ℃ in water[1,2].Au NRs has unique optical and photothermal effect.If PNIPAM or its copolymer are coupled with Au NRs,P(NIPAM-AM)@Au NRs would exhibit the excellent near-infrared controlled photothermal drug release property[3].