After many years of being a technology used solely by researchers and industrial evangelists,PAT is finally making a very real and exponentially growing impact on the manufacture of pharmaceuticals as more and more companies realise that you truly can have improved product quality whilst at the same time achieving a reduction in cost and manufacturing time.Furthermore,the holistic approach embraced by PAT is having a growing impact on manufacturing in the pharmaceutical,food and chemical industries,where the perhaps occasional use of unconnected and uncontrolled spectral instruments has been seen for many years.