【摘 要】
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Backgroud: Oxidative stress and inflammation play an important role in the development of the occurrence of Alzheimers Disease (AD).Thioredoxin binding protein-2 (TBP-2) is a oxidative stress and pro-
【机 构】
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Henan University of Traditional Chinese Medicine, Zhengzhou, China
【出 处】
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中国免疫学会第九届全国免疫学学术大会
论文部分内容阅读
Backgroud: Oxidative stress and inflammation play an important role in the development of the occurrence of Alzheimers Disease (AD).Thioredoxin binding protein-2 (TBP-2) is a oxidative stress and pro-inflammation factor.The role of receptor for advanced glycation end products (RAGE) and Aβ-induced oxidation stress are an key contributor to neurodegeneration in AD.However, the effect of them on the molecular mechanism of AD still unclear.We will present evidence for a novel pathway of TBP-2-RAGE in AD, which are inhibited by Liuweidihuangwan serum (LWDHS) to promote neuroprotection by blocking oxidative stress and inflammation in AD.
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