【摘 要】
：
Objective: To investigate the effect of pulmonary hemodynamics to endogenous nitric oxide(NO)in acute hypoxia rats.Methods: The non-selective nitric oxide synthase(NOS)inhibitor NG-nitro-L-arginine me
【机 构】
：
Medical college of Qinghai University,Xining,Qinghai,China
论文部分内容阅读
Objective: To investigate the effect of pulmonary hemodynamics to endogenous nitric oxide(NO)in acute hypoxia rats.Methods: The non-selective nitric oxide synthase(NOS)inhibitor NG-nitro-L-arginine methyl ester(L-NAME)was administered in anesthetized rats.In order to observed changes in pulmonary hemodynamics of rats,the central venous pressure(CVP),Systemic arterial pressure(Psa),pulmonary arterial pressure(PAP),left atrial pressure(LAP),aortic blood flow(ABF),and airway pressure(Paw)were directly and simultaneously measured in rats under normoxia(20.9%O2)and different hypoxia(17%O2、15%O2)respectively.
其他文献
Introduction:Reactive oxygen species(ROS)generally indicates single oxygen-containing electron substances with reducibility in organisms.And it participates in the mobilization of intracellular calciu
Calcium ion influx through CaV1.2 calcium channel is essential for the cardiac excitation contraction coupling and dysfunction of CaV1.2 channel will trigger the myocardial hypertrophy.Previously,we f
Introduction: The vascular pathological states in pulmonary hypertension(PH)owe much to an acute homeostasis imbalance of Ca2+in pulmonary arterial smooth muscle cells(PASMCs).The present research res
Background and Aim: Studies have revealed a relationship between erythrocytic antigens of the ABO and Rh blood systems and cardiovascular pathology.Reduced heart rate variability(HRV)indicates an incr
Introduction: A prolonged Q-T interval is associated with malignant ventricular arrhythmias.In cancer patients,drug induced cardiac toxicity and prolonged Q-T interval is well documented.But not much