A novel thermo-sensitive gel intervening in tumor microenvironment for controlled local delivery of

来源 :2014年中国药学大会暨第十四届中国药师周 | 被引量 : 0次 | 上传用户:lyun888
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  With the development of phage display,antibody engineering,monoclonal antibody(Mab) has become mature and the efficaciously route to therapy cancer in recent years due to its specificity to the tumor.Although the Mab become the important way in cancer treatment,it still has the limitations such as the instability,immunogenicity,relatively short half-life due to the essence of protein drug,and the systematic toxicity by intravenous infusion (Ⅳ).In practical,the local delivery system may be the potential way to avert the drawbacks.
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