目的 通过与安慰剂进行比较,评价开郁宁片治疗轻中度抑郁症(属肝气郁结证)的安全性和有效性.方法 采用多中心、随机、双盲、安慰剂平行对照的实验设计.疗程为6周.纳入符合ICD-10抑郁发作或复发性抑郁障碍或双相情感障碍有关轻、中度抑郁发作诊断标准、符合中医辨证属肝气郁结证的患者;年龄18-65岁,男女不限;筛查和基线的汉密尔顿抑郁量表(HAMD)17项评分≥17分且≤24分.试验药物为开郁宁片150
目的 比较双额极与单侧顶颞极无抽搐电痉挛治疗对精神分裂症认知功能的影响.方法 将60例精神分裂症患者随机分为两组,一组接受双额极(双侧组)无抽搐电痉挛治疗,另一组接受非优势半球单侧顶颞极(单侧组)无抽搐电痉挛治疗.共给予无抽搐电痉挛治疗8次,应用重复性成套神经心理状态测验手册在治疗前、治疗4次、6次、8次时进行认知功能检测.
目的 富马酸喹硫平作为第二代抗精神病药物,目前已更多的应用于情感障碍的治疗当中,作为情感稳定剂的增效剂,改善患者的睡眠情况.但在获得较好的临床疗效的同时,也会偶见一些严重的不良反应.报道一例富马酸喹硫平在治疗情感障碍时出现癫痫发作的案例,为临床治疗提供经验方法 观察富马酸喹硫平在使用过程中的副反应,及副反应与药物剂量之间的关系.
Background To evaluate the relationship between coronary artery remodeling and endogenous receptor for advanced glycation endproducts (esRAGE) in diabetic patients.Methods Intravascular ultrasound (IV
Background 3D QCA analysis may provide more accuracy in predicting functionally significant FFR and evaluating intermediate the severity of single coronary lesion.However,the performance of the dedica
Background Mounting evidence suggests that DNA damage is implicated in the development and the progression of atherosclerosis.To generate more information on genetic epistasis,we focused on six well-c
Background The impact of intravascular ultrasound (IVUS) guided coronary drug eluting stent (DES) implantation on clinical outcomes remains controversial.A meta-analysis of the currently available cli
Background To assess the potential relation between the number of circulating endothelial progenitor cells (EPCs) and plaque composition and severity of coronary culprit lesions using Virtual Histolog
Background Atrial septal defect (ASD) is one of the most common congenital heart diseases detected in adults.Along with remarkable development of device technology,the first treatment strategy of secu
Background Transcatheter aortic valve implantation (TAVI) has already becoming a supplementary option for elderly patients with serious comorbidity burdens.However,gender-related differences in compli