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Objectives Delay in the initiation of appropriate antifungal therapy is associated withsubstantial morbidity and mortality.The aim of this study was to derive a score risksystem for the development of invasive fungal infections in the intensive care unit(ICU).Method We retrospectively evaluated 1812 patients who stayed in the ICU for ≥4days,used univariate and multivariable logistic regression to identify potential riskfactors associated with invasive fungal infections (IFI),and created the risk scoresystem.