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5. A facile pH-sensitive shielding strategy for polycationic gene delivery system

A facile pH-sensitive shielding strategy for polycationic gene delivery system

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：yvonnechan

【摘 要】

：

Polycationic gene delivery system was widely used for cancer therapy.Polycations with high positive potentials exhibited good transfection efficiency,but at the same time,the surplus positive charges

【作 者】

：

Xiuwen Guan Ying Zhang Huayu Tian Xuesi Chen 

【机 构】

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Key Laboratory of Polymer Ecomaterials,Changchun Institute of Applied Chemistry,Chinese Academy of S

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

pH-sensitive PEGylation shielding gene delivery cancer therapy 

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　　Polycationic gene delivery system was widely used for cancer therapy.Polycations with high positive potentials exhibited good transfection efficiency,but at the same time,the surplus positive charges also induced undesirable cytotoxicity[1].

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