Real-Time Monitoring of Arsenic Trioxide Release and Delivery by Activatable T1 Imaging

来源 :纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会 | 被引量 : 0次 | 上传用户：pengweimin

【摘要】

：

【作者】

：

Zhenghuan Zhao Jinhao Gao

【机构】

：

State Key Laboratory of Physical Chemistry of Solid Surfaces, The Key Laboratory for Chemical Biolog

【出处】

：

纳米药物及纳米生物技术国际学术大会暨中国药学会纳米药物专业委员会成立大会

【发表日期】

：

2015年11期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Delivery of arsenic trioxide (ATO), a clinical anticancer drug, has drawn much attention to improve its pharmacokinetics and bioavailability for efficient cancer therapy.Real-time and in situ monitoring of ATO behaviors in vivo is highly desirable for efficient tumor treatment.Herein,we report an ATO-based multifunctional drug delivery system that efficiently delivers ATO to treat solid tumors and allows real-time monitoring of ATO release by activatable T1 imaging.

其他文献

Magnetoferritin: A Biomimetic Magnetic Nanoparticle with Intrinsic Tumor Targeting Ability for Cance

One of the major obstacles in clinical cancer intervention is the in vivo detection of tumors at pre-angiogenic stage, when the cancer is still confined to the site of origin and timely preventative t

会议

Multifunctional Encapsulations of Gold Nanoparticles as Nanotheranostic for Computed Tomography Imag

Despite many disadvantages, such as rapid in vivo circulation and renal toxicity, clinical iodine-based contrast agent cant be replaced by new contrast agent-gold nanoparticle (AuNPs) possessing high

会议

Novel Lanthanide-Polymer Complexes: Dye-Free Dual Model Probes for MRI and Fluorescent Imaging

High-resolution imaging is an powerful technique in theranostic and staging of tumors.[1]Dual-modal imaging using lanthanide hybrid nanoparticles as probes have been attracting increasing attention ba

会议

Multifunctional Protein Kinase CK2 Inhibitor Loaded Gold Nanoparticles for Simultaneous Cancer-Targe

Objective: Protein kinase CK2 is a multipotential serine/threonine kinase and plays multiple roles in the regulation of gene expression and cell proliferation [1].

会议

Protein kinase CK2QuinalizarinGold nanoparticles (AuNPs)cellular uptake

Non-Invasive in Vivo Targeting Human Pancreatic Cancer by Magnetic Resonance Imaging

The detection of cancer biomarkers is important for diagnosis, disease stage forecasting,and clinical management.[1] Pancreatic cancer (PC) is a devastating disease characterized by a very poor progno

会议

“Off-On” Switchable Sensor: a Near-Infrared Fluorescent pH Probe and Its Imaging Applications in Viv

Intracellular or extracellular pH is influenced by diverse physiological and pathological processes, so quantitatively measuring pH is useful for cellular analysis or diagnosis.In this work, a new nea

会议

One-Pot Synthesis of Magnetite-Loaded Dual Mesoporous Silica Spheres for T2-Weighted Magnetic Resona

Recently, integration of mesoporous silica nanoparticles (MSNs) and superparamagnetic nanocrystals to fabricate multifunctional platforms has great potential for simultaneous imaging and drug delivery

会议

One-Step Quantitative Detection of Human Chorionic Gonadotropin by Integrating Immunochromatography

During the past decade, a number of methods have been developed for tumor marker detection[1, 2].Although lots of advances have been achieved, detection methods are still severely restricted by their

会议

Paper-Based Colorimetric Analytical Device Based on Molecularly Imprinted Polymers

In this work, a colorimetric molecularly imprinted polymer sensor has been developed for the sensitive and selective detection of bisphenol A (BPA).The Pd/Fe3O4@C peroxidase mimetics was prepared in s

会议

Paper-Based Electrochemical Biosensor Detection Platform

Paper-based electrochemical biosensor platform represent a new generation of point-of-care diagnostic devices.Most disposable biosensors are made by non-degradable materials, such as PC, PVC and PET w

会议

Real-Time Monitoring of Arsenic Trioxide Release and Delivery by Activatable T1 Imaging

与本文相关的学术论文