【摘 要】
：
T-cadherin is a GPl-anchored member of cadherin superfamily.T-cadherin mediates guidance of migrating cells rather than cell-cell adhesion.Tumor growth and metastasis are dependent on cell movement an
【机 构】
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M.V.Lomonosov Moscow State University Russia
论文部分内容阅读
T-cadherin is a GPl-anchored member of cadherin superfamily.T-cadherin mediates guidance of migrating cells rather than cell-cell adhesion.Tumor growth and metastasis are dependent on cell movement and invasion, thus T-cadherin was suggested to be involved in cancer progression.In normal human skin T-cadherin was expressed in epidermis, blood vessels, and melanocytes but its expression was decreased during malignant transformation in primary melanomas and metastasis.
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