【摘 要】
：
Aims Drag-reducing polymers (DRPs) are blood-soluble macromolecules that can increase blood flow and reduce vascular resistance.The purpose of the present study is to observe the effect of DRPs on mon
【机 构】
：
Department of Cardiology, the Second Clinical Medical School of Yanghou University, Yangzhou, China
【出 处】
：
第17届中国南方国际心血管病学术会议
论文部分内容阅读
Aims Drag-reducing polymers (DRPs) are blood-soluble macromolecules that can increase blood flow and reduce vascular resistance.The purpose of the present study is to observe the effect of DRPs on monocrotaline-induced pulmonary hypertension (PH) in rat model.
其他文献
目的 观察荷叶生物碱对THP-1巨噬细胞CD36和PPARγ表达的影响,探讨荷叶生物碱干预CD36表达的信号传导途径.方法 THP-1细胞分化为巨噬细胞后,随机分为四组:空白对照组、ox-LDL组、荷叶生物碱组、环格列酮组.经四组干预后油红O染色观察,用Real-time PCR和Western Blot技术从mRNA和蛋白水平检测CD36及PPARγ的表达.
目的 老龄孤立性房颤的发病机制与异位起搏电流增强具有相关性,伊伐布雷定为起搏电流特异性抑制剂,对窦房结外其他部位心肌起搏电流具有抑制作用,本研究探讨伊伐布雷定对老龄房颤犬模型的心房电生理影响.方法 12条老龄比格犬随机分为2组,药物干预组6条,快速起搏组6条,12条犬均植入心房起搏器,经8周400次/分快速起搏造房颤模型.8周后测量房颤诱发率、校正窦房结恢复时间、心房各部位有效不应期、肺静脉有效不
Objective To investigate the effect of high glucose on the generation of ROS and the expression of Nrf2 of human umbilical vein endothelial cells (HUVEC).Methods: Human umbilical vein endothelial cell
目的 脑肾素-血管紧张素系统(RAS)及其新成员血管紧张素转换酶2(ACE2)是机体内调控血压水平和神经内分泌功能的最重要机制之一.大脑中的RAS系统通过其主要效应物质血管紧张素Ⅱ(Ang Ⅱ)参与脑海马脑源性神经营养因子(BDNF)信号调控过程.本研究旨在探讨高血压小鼠脑海马组织中BDNF与丝裂原活化蛋白激酶(MAPKs)信号改变及重组ACE2干预后对该信号通路的影响.
Objective Vascular calcification is a major feature of advanced atherosclerosis and highly associated with cardiovas cular diseases.Toll like receptor 4 (TLR4) is highly expressed in atherosclerotic l
Objective Cyclin-A2, which normally disappears after birth, is a key regulator of mammalian cell cycle.Fibrin glue is a common biological scaffold and wall support in ischemic myocardium.This study is
Aim Thiazolidinediones (TZDs), the antidiabetic agents such as ciglitazone, has been proved to be effective in limiting atherosclerotic events.However, its role in endothelial dysfunction (ED) remains
Objective Hypoxia causes cardiac disease via oxidative stress, mitochondrial dysfunction or protein misfolding and aggregation.Autophagy plays pathogenetic roles in eliminating damaged protein and mai
Objective To evaluate the expression changes of Bax and Bcl2 after spinal cord ischemia reperfusion injury (SCII) and exposition in the hypothermia during the operation in the rats.Methods 60 Rats wer
目的 研究整合素连接激酶(ILK)在大鼠离体心脏缺血再灌注室性心律失常中的作用及机制.方法 使用8-10周龄(200～230g)的雄性SD大鼠,采用Langendorff离体心脏灌注系统,结扎冠脉左前降支缺血30分钟,再灌注30分钟,建立缺血再灌注心律失常模型,予ILK活性调节剂预处理,监测大鼠缺血再灌注室性心律失常的变化,通过Western blot及免疫荧光染色法分析缝隙连接蛋白43(Cx43