【摘 要】
：
The heterogeneity of the tumour is a big obstacle for personalised therapy.Hepatocellular carcinoma(HCC) is an extraordinarily heterogeneous disease because, in
【机 构】
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InternationalCooperationLaboratoryonSignalTransduction,EasternHepatobiliarySurgeryInstitute/Hospital
【出 处】
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第一届自噬生物学与疾病国际研讨会(The 1st International Symposium on Autophag
论文部分内容阅读
The heterogeneity of the tumour is a big obstacle for personalised therapy.Hepatocellular carcinoma(HCC) is an extraordinarily heterogeneous disease because, in addition to the common intrinsic cancer heterogeneity resulting from genome instability, a number of epigenetic alterations occur, induced by host microenvironment and several aetiologies (virus infection, sexual susceptibility, metabolic disorder, gut microbiome, alcohol intake and nonalcoholic steatohepatitis).
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