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5. Repositioning of Artemisinin for Antitumor Agent:Discovery of Novel Spirobicyclic Analogues

Repositioning of Artemisinin for Antitumor Agent:Discovery of Novel Spirobicyclic Analogues

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：bright_123456789

【摘 要】

：

Artemisinin was used as a drug repositioning prototype for the development of novel antitumor drugs.Spiro-heterocycle unit as a core fragment has been found to exhibit wide range of activities in a va

【作 者】

：

Gang Liu Shanshan Song Zehong Miao Ao Zhang Chunyong Ding 

【机 构】

：

CAS Key Laboratory of Receptor Research,and Synthetic Organic & Medicinal Chemistry Laboratory

【出 处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

Drug repositioning Spirobicyclic analogues Antiprolifereative effect Preliminary 

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　　Artemisinin was used as a drug repositioning prototype for the development of novel antitumor drugs.Spiro-heterocycle unit as a core fragment has been found to exhibit wide range of activities in a variety of disease areas.

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