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目的 :观察男炎消对大鼠实验性前列腺炎的组织病理学影响。方法 :采用向大鼠前列腺组织内注入角叉菜胶的方法复制大鼠前列腺炎模型 ,并分别对模型组及口服男炎消冲剂后的大鼠组进行前列腺组织病理学检查。结果 :口服男炎消冲剂后的大鼠前列腺湿质量均比模型组明显要轻 ,两者比较有统计学差异 (P <0 .0 5) ,且镜下炎症改变亦比模型组明显轻。结论 :口服男炎消冲剂对角叉菜胶所致大鼠实验性前列腺炎具有较好的抑制炎症发生作用。
Objective : To observe the histopathological effects of male Yanxiao on experimental prostatitis in rats. METHODS: Rat prostatitis model was established by intraperitoneal injection of carrageenan into rats’ prostate tissue. Prostate histopathological examinations were performed on the model group and the rats group after oral administration of male granules. RESULTS: The wet weight of rat prostate after oral administration of male-inflammation-eliminating agent was significantly lower than that of the model group. There was a statistically significant difference between the two groups (P < 0.05), and the microscopic inflammation was also significantly lighter than that of the model group. Conclusion : Oral administration of male yanxiao granules can effectively inhibit inflammation in rat experimental prostatitis induced by carrageenan.