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  5. Calcitriol inhibits bleomycin-evoked early pulmonary inflammatory response and epithelial-mesenchyma

Calcitriol inhibits bleomycin-evoked early pulmonary inflammatory response and epithelial-mesenchyma

来源 :中华预防医学会自由基预防医学专业委员会2015年夏季学术交流会 | 被引量 : 0次 | 上传用户：tiancejiangjun
【摘 要】
：
　　Early pulmonary inflammation and epithelial-mesenchymal transition(EMT)play an important role in the pathogenesis of bleomycin(BLM)-induced lung fibrosis.In
【作 者】
：
Zhu-XiaTan[1]Yuan-HuaChen[2]ShenXu[1]Hou-YingQin[1]ChengZhang[2]HuiZhao[1]De-XiangXu[2] 
【机 构】
：
Second Affiliated Hospital,Anhui Medical University,Hefei 230032,China
【出 处】
：
中华预防医学会自由基预防医学专业委员会2015年夏季学术交流会
【发表日期】
：
2015年期
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论文部分内容阅读
　　Early pulmonary inflammation and epithelial-mesenchymal transition(EMT)play an important role in the pathogenesis of bleomycin(BLM)-induced lung fibrosis.Increasing evidence demonstrates that calcitriol,the active form of vitamin D3,has an anti-inflammatory activity.The present study investigated the effects of calcitriol on BLM-induced pulmonary inflammation and EMT.
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