CD4+Foxp3+ Tregs protect against innate immune cell-mediated fulminant hepatitis in a C57BL/6 mice m

来源 :中国免疫学会第九届全国免疫学学术大会 | 被引量 : 0次 | 上传用户:dylwq
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Background and Aims: Foxp3+ Tregs are important for maintaining homeostasis by controlling excessive immune responses that cause serious tissue damage;yet, relatively little is known about the impact of Tregs on innate immune cells in hepatitis models in vivo.In this study, we examined the role of hepatic Tregs in innate immune-mediated liver injury.Methods: A mouse model for innate immune-mediated fulminant hepatitis was established by injection polyI∶C and D-galactosamine (D-GalN) into C57BL/6 mouse.
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