The pharmaceutical quality control is of great importance for maximizing the efficacy and the safety of the drug therapy and the economy of the production of drug.Pharmacological and toxicological characteristics often vary between enantiomers of the racemic drug because of the enantioselective biological interactions and reactions.One of them may be the most active enantiomer while the other may generate side-effects and/or toxicity.Thus, the determination of individual enantiomers is necessary for monitoring the pharmacokinetics and pharmacodynarnics of chiral drugs.