Purpose: To determine the signaling pathways involved in chondrocyte migration and their effects on cartilage integration in autologous chondrocyte implantation.
目的：探讨p38MAPK与假体周围颗粒诱导炎性骨溶解之间的关系.方法：钛颗粒刺激体外培养的RAW246.7细胞,用SB203580干预,Western blot检测p-p38mapk蛋白表达,ELISA检测细胞分泌TNF-a,IL-6水平.结果：钛颗粒刺激细胞培养组(B组)比较于没有用颗粒刺激的正常培养组(A组),p-p38mapk蛋白含量,以及培养液上清中TNF-a,IL-6含量都明显升高(p＜
Introduction: Hydroxyapatite (HA) has been studied recently as a drug carrier in prevent implant infections due to its biocompatibility and osteoconductive properties, but most of these studies failed
Objective To study the osteogenic potential of SF/PLCL electrospinning material composited with bone mesenchymal stem cells (BMSCs) in repairing the radius defection in rabbits.Method Bone marrow was
Objective: To investigate the effect of BMSCs transplantation on adrenocorticotropic hormone and AMPA receptors in rats with SCI and elucidate the potential anti-chronic stress mechanism of BMSCs tran
Aim: This study aimed to investigate the biocompatibility and osteogenesis capacity of a novel Sema3A CMs/SF/α-TCP composite material in vitro.Materials and Methods: Sema3A was incorporated into CMs,
目的:探讨应用Prestige LP人工椎间盘置换治疗颈椎病的初期疗效.方法:采用Prestige LP人工颈椎间盘置换术治疗颈椎病患者14例,统计并分析患者术前和术后随访时相关指标并进行比较.结果:所有患者均为单节段置换,术后随访平均15.6个月.术后JOA评分由(10.3±2.1)提高到(15.2±4.4),NDI评分由(42.30±10.15)％提高到(16.54±8.16)％,颈部疼痛VA
目的:分析采用高粘度骨水泥及其椎体成形手术系统治疗重度骨质疏松性胸腰椎骨折的疗效.方法:回顾分析本院2012年6月至2013年6月采用高粘度骨水泥及其椎体成形手术系统治疗的12例重度骨质疏松性胸腰椎压缩性骨折患者临床资料,手术前后采用目测类比评分评估腰背部疼痛、ODI评分评估腰背部功能、SF-36健康调查评分表评估生活质量、Frankel评分评估神经功能,影像学测量伤椎椎体高度％、伤椎后凸角度等参
目的:探讨在原发性腰椎管内肿瘤切除手术中使用改良棘突椎板复合体回植的方法和效果.方法:回顾我院2010年1月-2013年7月收治的24例原发性腰椎管内肿瘤患者,术中用微锯切断双侧椎板,保留双侧关节突,切断一侧棘上和棘间韧带,临时固定于一端,显微镜下摘除肿瘤,将带蒂棘突椎板复合体原位回植,选取微型钛板固定.结果:所有患者肿瘤成功切除,未出现脑脊液漏,无顽固性下腰痛,钛板固定可靠,回植椎板无塌陷,能有
目的：探讨采用Quadrant通道下单侧椎体间减压融合内固定结合对侧经皮椎弓根螺钉内固定治疗腰椎退变性疾病的方法及疗效.方法：2009年9月至2012年12月，采用Quadrant通道下单侧PLIF技术结合对侧经皮椎弓根螺钉内固定微创治疗腰椎退变性疾病共20例.男8例，女12例；年龄45～ 66岁，平均57.5岁.病程1～8年，平均36.5个月.腰椎间盘突出症11例，复发性腰椎间盘突出症4例，腰椎