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Based on our understanding of mechanism of leukomo-carcinogenesis and on recent progressions of cancer invasive and metastastic investigations in literatures, and also on success experiences in gene therapy for rat MDS and early esopheagical cancer, the author presents his therapeutic strategy for advanced cancers which includes 2 schemes: first,patients will be administrated 3 oncogenes (V-erbB, C-Met and TS) product inhibitors, such as TKIs and 5-Fu to kill most cancer cells;second, patients will be given two oligodeoxynucleotides (antigene V-erbB and CpG ODN) for treatment of cancer stem cells and residual cancer cells in order to prevent cancer relapse and metastasis and this will continue up to more than 5 years till the complete remission or full cure.This therapy could be named as Gene Product Therapy and Gene Therapy as well.We hope it may be improved and perfected in practice.