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目的 Theaimofthestudywastodeterminetheeffectsofplasminogenactivatorinhibitortype-1(PAI-1)onmesenchymalstemcellinLPS-inducedacutelunginjury.方法 Invivo,wildtype(WT)micewererandomlydividedinto4groups：PBSgroup,LPSgroup,humanembryoniclungfibroblastcells(HELFs)groupandhumanmesenchymalstemcells(MSCs)group(n=5pergroup).