Pyrone derivatives from the endophytic fungus Alternaria tenuissima SP-07 of Chinese herbal medicine

来源 :中国化学会第十届全国天然有机化学学术会议 | 被引量 : 0次 | 上传用户:long_drago
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Three new pyrones, solanapyrones P-R (1-3), were afforded by the extracts of the endophytic fungus Alternaria tenuissima SP-07 isolated from the fresh root of Chinese herbal medicine Salvia przewalskii1, along with the known solanapyrones A-C (4-6, resp.), alternariol (7), alternariol methyl ether (8), and altenuene (9).
其他文献
The genus Excoecaria (Euphorbiaceae) comprises of nearly 40 species, distributed throughout tropical, Asia and northwest Australia.Seven species are found in China, of which E.cochinchinensis, E.agall
会议
The nuclear factor-κB (NF-κB), a ubiquitously expressed proinflammatory transcription factor,plays a crucial role in cell growth, apoptosis and tumorigenesis, and it makes the NF-κB signaling pathway
会议
OSW-1 is a cholestane glycoside isolated from the bulbs of Ornithogalum saundersiae, which has exhibited exceptionally potent cytotoxicities against various malignant tumor cells1-3.Recent studies hav
会议
黄芪素(Baicalein)又名黄芩苷元,对多种疾病包括炎症、肿瘤、纤维化性疾病、心脑血管性疾病以及神经性疾病具有良好的防治作用1-2.由于黄芩素水溶性和脂溶性比较差,在一定程度上限制黄芩素的临床应用范围.因此,本文以黄芩素为先导化合物对其进行结构修饰,采用拼合原理将具有抗炎、镇痛活性药物布洛芬与黄芩素进行拼合,改善黄芩素的脂溶性,并提高黄芩素的抗炎活性,期望扩大黄芩素临床应用范围.
会议
The fluorinated molecules have found increasing applications in different fields, such as medicinal and materials chemistry1.Due to the containing of "-CHF-S-" moiety, the α-fluoro-sulfides can be use
会议
为了探讨加味白头翁汤起效的物质基础及其在体内的作用靶标,采用系统分离纯化的方法,对加味白头翁汤总提物的化学成分进行了较系统的研究.通过MCI大孔吸附树脂柱层析、硅胶柱层析、C18开放柱和制备液相等共分离得到42个化合物,通过HR-ESI-MS、13CNMR 等波谱技术以及化学方法,鉴定了其中38个化合物的结构.本文利用UPLC-QTOF-MSE对加味白头翁汤中的化合物进行了结构分析,并通过UPLC
会议
小芸木(Micromelum integerrimum var.integerrimum)为芸香科(Rutaceae)小芸木属植物.本属植物全世界约10种,我国有2种及1个变种,即大管小芸木M.falcatum及变种毛叶小芸木M.integerrimum var.mollissimum,分布于广东、广西、云南三省区南部,西藏东南部和海南1.本属植物全株用药,多用其根,具有行气、散瘀和活血等功效,治
会议
Wood plant Schima superba (Theaceae) is widely distributed in southeast Asian.The plant is known locally as "Mu He" in southeast mainland and also is an important timber resource.Its stem bark has bee
会议
Many plants in Senecio are used as traditional Chinese medicines.Senecio have been studied for their bio-activities, such as antioxidation, antivirus effect, bacteriostrasis effect and antitumor activ
会议
Two new triterpene saponins, ilexpublesnin N (1) and ilexpublesnin O (2), along with five known saponins were isolated from the roots of Ilex pubescens.Their structures were elucidated on the basis of
会议