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5. Ynamide-Mediated Thioamide Substituted Peptide Synthesis

Ynamide-Mediated Thioamide Substituted Peptide Synthesis

来源 :第十一届全国化学生物学学术会议 | 被引量 : 0次 | 上传用户：jackzeng6699

【摘 要】

：

Thioamide substitution has evolved into an important tool for the chemical biology of peptides and proteins.[1] However,exploration of its full potential has been hampered by insufficient synthetic st

【作 者】

：

Junfeng Zhao 

【机 构】

：

College of Chemistry and Chemical Engineering,Jiangxi Normal University,Nanchang,330022,Jiangxi,P.R.

【出 处】

：

第十一届全国化学生物学学术会议

【发表日期】

：

2019年3期

【关键词】

：

Ynamide thioacylating reagent solid phase peptide synthesis thioamide 

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　　Thioamide substitution has evolved into an important tool for the chemical biology of peptides and proteins.[1] However,exploration of its full potential has been hampered by insufficient synthetic strategies for site-specific introduction of a thioamide bond to a peptide backbone.

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