抗体免疫压力下猪繁殖与呼吸综合征病毒ORF3和ORF5基因变异研究

来源 :2013国际猪繁殖与呼吸综合征学术研讨会 | 被引量 : 0次 | 上传用户：xsyangle

【摘要】

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引言猪繁殖与呼吸综合征(PRRS)是广泛流行于世界各养猪国家的重要繁殖障碍性病毒病之一,目前此病无有效的治疗手段,最常用的就是疫苗免疫等综合防治措施.已有研究证明,有些病毒在抗体选择压下会发生基因变异并能导致抗原性改变,从而逃避宿主的免疫系统.本研究旨在对猪繁殖与呼吸综合征病毒(PRRSV)在抗体免疫选择压力下是否发生变异进行研究.材料与方法将HPPRRSV-JXAl株在添加适量抗体或不添加抗

【作者】

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贺东生陈瑞爱牛晓芸王艳丽熊志轩张显浩

【机构】

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广东省兽用生物制品技术研究与应用企业重点实验室,广东肇庆526238;华南农业大学兽医学院,广东广州510642

【出处】

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2013国际猪繁殖与呼吸综合征学术研讨会

【发表日期】

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2013年12期

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抗体免疫压力下猪繁殖与呼吸综合征病毒ORF3和ORF5基因变异研究

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