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结核病是由结核杆菌复合群(mycobacterium tuberculosis complex,MTBC)引起的慢性感染性疾病。据世界卫生组织统计,全世界结核病每年新增病例870万左右,其中,110万人合并HIV感染[1]。目前,主要依靠有效的疫苗、精确的诊断技术及合理的药物治疗等方法对结核病进行有效的控制。然而,由于机体对结核杆菌(M.tuberculosis,MTB)免疫反应的复杂性,致使目前为止对新型结核疫苗的评价、结核感染的诊断和
Tuberculosis is a chronic infectious disease caused by the mycobacterium tuberculosis complex (MTBC). According to the statistics of the World Health Organization, there are about 8.7 million new cases of tuberculosis worldwide each year, of which 1.1 million people are infected with HIV. [1] At present, the effective control of tuberculosis depends mainly on effective vaccines, accurate diagnosis techniques and reasonable drug treatment. However, due to the complexity of the body’s immune response to M. tuberculosis (MTB), the evaluation of new TB vaccines so far, the diagnosis of TB infection and