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  5. Loss of classical transient receptor potential 6 channel reduces ozone-induced airway inflammation

Loss of classical transient receptor potential 6 channel reduces ozone-induced airway inflammation

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户：tscy123
【摘 要】
：
Background: Ozone exposure can cause lipid peroxidation which leads to diacylglycerol accumulation.Diacylglycerol mediated endotoxin-induced lung inflammation through activation of TRPC6(canonical tra
【作 者】
：
Yubo Zhou Qingzi Chen Zhaodi Fu Lifen Zhou Jianhua Li 
【机 构】
：
Department of Physiology,Guangzhou Medical University,Guangzhou,511436,China
【出 处】
：
2016年国际生理学学术大会
【发表日期】
：
2016年6期
【关键词】
：
airway inflammation ozone exposure TRPC6 
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　　Background: Ozone exposure can cause lipid peroxidation which leads to diacylglycerol accumulation.Diacylglycerol mediated endotoxin-induced lung inflammation through activation of TRPC6(canonical transient receptor potential channel 6).TRPC6 is highly expressed in the lung.However,its role in ozone-induced airway inflammation remains poorly understood.
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