Objective Cancer is defined as the second leading cause of death and has become a huge global health burden.The discovery and development of novel and efficient anticancer drugs or strategies for trea
Objective Over 20%of cancer driver genes encode chromatin regulators.LncRNAs which were misregulated in various cancers play critical role in chromatin dynamics and gene regulation by interacting with
Objective Doxorubicin(DOX)is a chemotherapy medication used to treat various cancers.However,cardiotoxic side effects limit their dosing and improved cancer outcomes.
Objective Hepatocellular carcinoma(HCC)is the most lethal primary liver cancer known for limited available treatments.The development of novel anti-HCC agents is important.
Objective Colorectal cancer remains a leading malignancy in humans.The importance of epigenetic modification in the development of this disease is now being recognized.
Objective Androgen deprivation therapy(ADT)with antiandrogens targeting androgens/androgen receptor(AR)signaling is the standard used to treat prostate cancer in different clinical settings besides su