Since the introduction of the first biologic therapy for rheumatoid arthritis just over a decade ago, 9 drugs have been approved for registration, including 5 TNF inhibitors.Their general acceptance a
Alzheimers disease (AD) is the most common neurodegenerative disorders.Amyloid β-protein (Aβ) has been recognized as the leading cause of AD, and Aβ oligomer plays an important role in the early stage
Elevated serum IgE is a hallmark of allergic diseases such as asthma, and the neutralization of serum IgE in moderateto-severe allergic asthmatics using a therapeutic monoclonal anti-IgE antibody sign
Human Cripto-1 is a cell surface protein belonging to the EGF-Cripto-FRL-1-Cryptic (EGF-CFC) gene family that has been shown to play key roles in embryonic development and in tumor progression.CRIPTO-
Analysis of VH and VL sequences of conventional antibodies from camelids reveals a surprising high degree of sequence homology with human segments.In silico prediction suggests identical canonical fol
As the leading biotechnology company worldwide, Roche is committed in developing the next generation of first-inClass/Best in Class antibody therapies.We integrate deep insight in the disease biology
Hemorrhagic fever with renal syndrome(HFRS) is a kind of acute infectious disease which infected by Hanta virus(HV) and spreaded world-wide.Up to now there were no specific options available for treat
Human papillomavirus 16/18/58/6/11 L 1 VLPs were produced in baculovirus expression system.Mice were immunized with these types of VLPs respectively, and were used to develop monoclonal antibodies.We
目的：探讨青年颈椎病的临床影像学特点及手术治疗策略.方法：2006年1月～2009年12月在北医三院骨科颈椎组住院治疗的30岁以下的颈椎病患者36例,其中男性28例,女性8例；年龄17-30岁,平均27岁,职员7例,工人5例,农民2例,学生2例.无固定职业者11例,国家公务员6例,教师2例,医师1例.发病时间从1-84个月,平均15.7个月.回顾性分析患者的发病过程,临床及影像学表现,手术入路选择
Direct removal of the ossified mass via anterior approach carries good decompression to ossification of the posterior longitudinal ligament (OPLL) in the cervical spine.Ossification occasionally invol