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目的 Wesummarizetheclinicaldataofthispopulationandtheirsensitivitytofirst-,orsecond-lineEGFRTKItherapy.方法 AdvancedNSCLCpatientswith19delor21L858RwhousedtoreceiveEGFRTKIasfirst-,orsecond-linetherapyinShanghaiChestHospitalwereidentified.