Multifunctional Superparamagnetic iron Oxide Nanoparticles Loaded With Indocyanine Green for Potenti

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：bbcat1982

【摘要】

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【作者】

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Yan Ma Sheng Tong Gang Bao Zhifei Dai

【机构】

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Nanomedicine and Biosensor Laboratory,Bio-X Center,Harbin Institute of Technology,Harbin,150080,Chin

【出处】

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International Conference on Nanoscience & Technology,China 2

【发表日期】

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2013年3期

【关键词】

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Indocyanine green SPIO nanoparticles MRI imaging Fluorescence imaging Phototherm

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　　We discribe a novel multifunctional theranostic agent for bi-mode magnetic resonance imaging, fluorescent imaging and photothermal therapy by loading ICG molecules into the lipid layer of super paramagnetic iron oxide nanoparticles (ICG@SPIO Nps) for tumor dianosis and treatment.UV-vis spectra of ICG@SPIO NPs loaded with various amount of ICG verifies the successful loading of ICG and the ICG@SPIO NPs exhibit high encapsulation efficiency and loading capacity toward ICG.TEM images and DLS measurements show ICG@SPIO NPs disperse well in water and have an average diameter of 27.4 nm.

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Multifunctional Superparamagnetic iron Oxide Nanoparticles Loaded With Indocyanine Green for Potenti

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