【摘 要】
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Aim: Medicinal plant extracts are alternative sources of promising anti-cancer compound such as Plumbago extracts.Therefore, this study aims to investigate the effect of plumbagin on protein expressio
【机 构】
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International College of Medicine,Thammasat University,Pathumthani 12121,Thailand
【出 处】
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The 12th Meeting of the Asia Pacific Federation of Pharmacol
论文部分内容阅读
Aim: Medicinal plant extracts are alternative sources of promising anti-cancer compound such as Plumbago extracts.Therefore, this study aims to investigate the effect of plumbagin on protein expression in CCA cell line namely CL6.Methods: The CL6 cells were treated with plumbagin compound for 48 h.The cells were harvested at 0, 1, 3, 6, 12, 24, and 48 h, protein extracted, and subjected for LCMS/MS analysis.Results: Differential protein expression has been observed.To identification of up-and down-regulated protein will be analyzed by using DeCyder, MASCOT, and Mev software.Conclusion: This protein profile will be useful for anti-CCA drug development.
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