T和NK/T细胞淋巴瘤病人外周血单个核细胞中PD-1,CTLA-4,BTLA过表达

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：sunfeaml

【摘要】

：

目的：前期研究发现T和K/T细胞淋巴瘤病人外周血TCR信号通路分子表达缺陷等。近期发现T细胞抑制性受体如程序性凋亡因子(PD-1)、细胞毒性T淋巴细胞相关抗原(CTLA-4)、B和T淋巴细胞弱化因子(BTLA)等异常表达与肿瘤病人免疫功能缺陷密切相关。本研究分析T和NK/T细胞淋巴瘤病人外周血PD-1,PD-L1,CTLA-4和BTLA表达情况。

【作者】

：

廖紫薇吕学文王旭陈少华杨力建王亮吴秀丽李萡李扬秋

【机构】

：

暨南大学血液病研究所广东省农垦中心医院肿瘤科

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年10期

【关键词】

：

T细胞淋巴瘤 NK/T细胞淋巴瘤 PD-1 CTLA-4 BTLA

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T和NK/T细胞淋巴瘤病人外周血单个核细胞中PD-1,CTLA-4,BTLA过表达

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