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5. OP9-Lhx2 stromal cells facilitate derivation of hematopoietic progenitors both in vitro and in vivo

OP9-Lhx2 stromal cells facilitate derivation of hematopoietic progenitors both in vitro and in vivo

来源 :第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会 | 被引量 : 0次 | 上传用户：jackywang1980

【摘 要】

：

　　Generating engraftable hematopoietic stem cells(HSCs)from pluripotent stem cells(PSCs)is an ideal approach for obtaining induced HSCs for cell therapy.Howev

【作 者】

：

Xiaoli Chen Qianhao Zhao Chen Li Yang Geng Ke Huang Jian Zhang Xiaoshan Wang Jiaqi Yang Tongjie Wang Chengxiang Xia Xiaofei Liu MinghuiMeng Dan Yang Yi Zheng Juan Du Xiangzhong Zhang Jiekai Chen Guang 

【机 构】

：

KeyLaboratoryofRegenerativeBiology,GuangzhouInstitutesofBiomedicineandHealth,ChineseAcademyofScience

【出 处】

：

第八届广州国际干细胞与再生医学论坛暨第四届中国再生细胞生物学年会

【发表日期】

：

2015年12期

【关键词】

：

Hematopoietic progenitors Pluripotent stem cells OP9 Teratoma Lhx2 

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论文部分内容阅读

　　Generating engraftable hematopoietic stem cells(HSCs)from pluripotent stem cells(PSCs)is an ideal approach for obtaining induced HSCs for cell therapy.However,the path from PSCs to robustly induced HSCs(iHSCs)in vitro remains elusive.

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