【摘 要】
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In recent years,"compact molecules"e.g.4-membered heterocyclic compounds have received increased attention in pharmaceutical industry because of the uniqueness in the generation of IP position,as well
【机 构】
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Department of Medicinal Chemistry,School of Pharmacy,Fudan University,Shanghai201203
【出 处】
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第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
论文部分内容阅读
In recent years,"compact molecules"e.g.4-membered heterocyclic compounds have received increased attention in pharmaceutical industry because of the uniqueness in the generation of IP position,as well as adjustment of physical properties e.g.solubility,permeability,and safety related properties.The bottle necks of the application of such"compact molecules"are the difficult synthesis and scale-up.
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