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5. DL0707 inhibits balloon injury(BI)-induced carotid intimal hyperplasis in rats by regulating CREB an

DL0707 inhibits balloon injury(BI)-induced carotid intimal hyperplasis in rats by regulating CREB an

来源 :The 6th China-Russia International Conference on Medicine(第六 | 被引量 : 0次 | 上传用户：lconan

【摘 要】

：

Aim: As a typical polyphenol, DL0707 was confirmed to inhibit the proliferation and migration of vascular smooth muscle cells induced by platelet-derived growth factor-BB (PDGF-BB).Further experiments

【作 者】

：

RuiZhao Lan Sun Jun-ke Song Tao Xie Guan-hua Du 

【机 构】

：

National Center for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medica

【出 处】

：

The 6th China-Russia International Conference on Medicine(第六

【发表日期】

：

2014年3期

【关键词】

：

DL0707 Polyphenols BI Restenosis CREB p21/cip1 

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Aim: As a typical polyphenol, DL0707 was confirmed to inhibit the proliferation and migration of vascular smooth muscle cells induced by platelet-derived growth factor-BB (PDGF-BB).Further experiments were designed to testify the anti-restenosis effects of DL0707 in vivo and figure out the underlying mechanisms.

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