核糖体蛋白RACK1的O-GlcNAc糖基化促进肝细胞癌的上皮间质转化和转移

来源 :中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议 | 被引量 : 0次 | 上传用户：testjmalt

【摘要】

：

肝细胞癌(Hepatoeellular carcinoma,HCC)是世界范围内最常见并且最具有侵袭性的恶性肿瘤之一,我们之前研究发现核糖体RACK1(Receptor for activated C-kinase 1)可以促进肝

【作者】

：

顾建新

【机构】

：

复旦大学基础医学院卫生部糖复合物重点实验室,上海200032

【出处】

：

中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议

【发表日期】

：

2014年8期

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肝细胞癌(Hepatoeellular carcinoma,HCC)是世界范围内最常见并且最具有侵袭性的恶性肿瘤之一,我们之前研究发现核糖体RACK1(Receptor for activated C-kinase 1)可以促进肝细胞癌的增殖和化疗抵抗.然而,核糖体RACK1的功能如何被调节并不清楚.

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核糖体蛋白RACK1的O-GlcNAc糖基化促进肝细胞癌的上皮间质转化和转移

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