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  5. Transplantation of human endometrial stem cells into rodent mocardial infarct mediates tissue salvag

Transplantation of human endometrial stem cells into rodent mocardial infarct mediates tissue salvag

来源 :第11届中国介入心脏病学大会 | 被引量 : 0次 | 上传用户：QQainigirl
【摘 要】
：
Background Human menstrual blood stem cells (MBSCs) have the potential to be "off the shelf" clinical reagents.Here, we first studied MBSC therapy in an immunocompetent rat model of myocardial infarct
【作 者】
：
JIANG Zhi HU Xin-yang YU Hong XU Yin-chuan WANG Jian-an 
【机 构】
：
Department of Cardiology,Key Lab of Cardiovascular Disease,2nd Affiliated Hospital of Zhejiang Unive
【出 处】
：
第11届中国介入心脏病学大会
【发表日期】
：
2013年7期
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论文部分内容阅读
Background Human menstrual blood stem cells (MBSCs) have the potential to be "off the shelf" clinical reagents.Here, we first studied MBSC therapy in an immunocompetent rat model of myocardial infarction (MI).Methods The cytokine expression of human MBSCs and the effect on cell proliferation and apoptosis were measured in vitro.MBSCs were intramyocardially injected into the infarct border zone of Sprague-Dawly rats 30 minutes after coronary ligation.Echocardiography, microPET and histological study were performed 4 weeks after transplantation.
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