Chronic lymphocytic leukemia (CLL) with t(14;18)(q32;q21), a possible under-diagnosed and under-reco

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户:caesarsarahluckgirl
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Introduction Chronic lymphocytic leukemia (CLL) is the most common form of leukemia in the Western countries (1).The diagnosis of CLL is based on presence of > 5 x109cells/L neoplastic B-cells in the peripheral blood with characteristic morphologic and immunophenotypic features.Typically,CLL cells are small lymphocytes with round nuclei,clumped chromatin,scantc ytoplasm,and express CD5,CD23,CD20 (dim),CD22 (dim),and immunoglobulin light chain(dim),with CD10 and FMC-7 being negative.
其他文献
Objective Acute myeloid leukemia (AML) with mutated CCAAT/enhancer binding protein alpha(CEBPA) has recently been included in the WHO classification due to its prognostically favorable influence.Howev
会议
Background Epidermal growth factor receptor pathway substrate No.8 (EPS8) is a substrate binding to the juxtamembrane region of EGFR.Recent studies showed that the over- expression of EPS8 plays an im
会议
Aims To detect the expression of TRAIL,TRAIL receptor 1(DR4),TRAIL receptor 2 (DR5),TRAIL receptor 3 (Decoy receptor 1,DcR 1) and TRAIL receptor 4 (Decoy receptor 2,DcR2) on leukemic cells of patients
会议
Background Elderly acute myelocytic leukemia (AML) patients have limited treatment options because they poorly tolerate standard-dose chemotherapy.Here,we describe our experience with ultra-low dose d
会议
Acute myeloid leukemia (AML) is a malignant disease not sensitive to chemotherapy.The dynamic interaction between AML cells and bone marrow (BM) microenvironment plays a critical role in response of t
会议
Objective To evaluate the role of FLT3 gene mutations in acute promyelocytic leukemia (APL)patients with extramedullary relapse.Methods Retrospective analysis of the involved blood and bone marrow sam
会议
Objective To explore the clinical and laboratory characteristics of of APL patients with atypical FISH signal modes of PML-RARa.Method 52 patients with newly diagnosed APL were detected by DCDF-FISH f
会议
[研究背景]坊間從不乏教導我們如何成功、賺進人生第一桶金的書籍,但卻少有課程告知如何面對最後一段人生,加上國人避談死亡議題,因此當疾病或突來意外發生且無法恢復的關鍵時刻,常面臨難以進行醫療決策之窘境.國內推廣安寧護多年,但國人預立醫療指示(以下簡稱ACP)主宰醫療人生之意願表達仍不足,常造成臨床照護困難與家屬間之爭執.[研究目的]1.提升安寧療護認知.2.提升ACP 意願書簽署數.[研究方法方法]
目的 美國從1995 年起就參考航空界的CRM(Crew Resource Management)訓練模式來進行不同醫療專業間的團隊訓練課程,以促進團隊合作,並將此手法運用於病人安全的相關議題上.醫策會於2008 年將CRM 引進台灣,將之定名為團隊資源管理(Team Resource Management,TRM),並於醫院間積極推廣.胸腔內科病房的住院病人平均年齡超過65 歲,跌倒是此年齡層住
会议
Objective This study was to investigate the effect of 5-Aza-2-deoxycytidine (decitabine;DAC)and all-trans retinoic acid (ATRA) on the expression of p16INK4a(p16) and retinoic acid receptor β(RARβ),as
会议