【摘 要】
：
[Objectives] Placental hypoxic-ischemic pathology is one of the common causes for maternal and infant diseases.Non-specofic placental morphological and histopathological measures have been generally u
【机 构】
：
Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health,Xinhua Hospital,Sh
论文部分内容阅读
[Objectives] Placental hypoxic-ischemic pathology is one of the common causes for maternal and infant diseases.Non-specofic placental morphological and histopathological measures have been generally used in placental pathology evaluation.The aim of this study was to identify placental hypoxic-ischemic measures that have implications in long-term child health outcomes.
其他文献
在各种体内外因素的作用下，正常妊娠会发展为妊娠期高血压疾病，严重影响母儿安全。然而，妊娠期高血压疾病病因至今尚未完全阐明。国内外研究主要集中在子痫前期-子痫的病因和发病机制。
[目的] 用微阵列的比较基因组杂交技术(aCGH)诊断患儿及孕期胎儿染色体微小缺失、重复等异常.[方法]1)病例资料:2014年5月至2015年3月收集的135例样本,包括外周血84例、脐带血16例、绒毛6例、羊水24例和胎儿皮肤或肌肉组织5例.大部分样本进行染色体核型分析和常见染色体数目异常的FISH检测,用于基因组分析样本均为FISH不能检出的异常.2)基因组分析: (1)提取基因组DNA并纯
[目的] 研究整合素连接激酶(ILK)在新生鼠缺氧缺血性脑损伤(HIBD)后表达及变化.探讨ILK/磷酸化蛋白激酶B(p-Akt)信号通路在HIBD修复中的作用.
[目的] 研究妊娠期糖尿病孕妇与同期正常妊娠的孕妇网膜下脂肪组织中差异表达基因,探讨这些差异基因是否参与妊娠糖尿病的发生和发展,为探讨妊娠糖尿病的致病机理提供线索.[方法] 收集3例通过OGTT实验确诊但未经过治疗的妊娠期糖尿病患者和同期3例年龄,孕次产次,孕前BMI与之无差异的健康对照者网膜下脂肪组织,提取总RNA后,采用Affymetrix mRNA表达谱芯片进行检测,并进行基因表达谱结果进行
Imprinting disorders, such as Beckwith-Wiedemann syndrome (BWS) , Prader-Willi syndrome (PWS) andAngelman syndrome (AS) , can be detected via methylation analysis,methylation-specific multiplex ligati
Whole-genome microarray analysis is proven to be useful in the identification of submicroscopic copy number imbalances in families with intellectual disabilities.
Urinary Incontinence was acknowledged in 1998 by World Health Organization as a disease.To raise the awareness of the condition,literature suggests that 50% of the incontinent women would be under 50
[目的] 了解GDM孕产妇产后的血糖情况,孕期空腹血糖异常对产后血糖异常的影响.[方法] 随访2013年1月至2014年11月住院分娩的GDM孕产妇,于产后6-12周复查OGTT.[结果] 23个月内分娩2 388例GDM孕妇,其中1322例孕妇返回医院行OGTT检测,其中诊断DM26例,空腹血糖受损和糖耐量受损共231例.＜25岁年龄组产妇血糖异常检出率最低,为11.1％;≥35岁组血糖异常检出
[目的] 研究胰岛素样生长因子-1(IGF-1)对新生小鼠缺氧缺血性脑损伤(HIBD) 48小时内脑海马细胞线粒体膜电位(DYm)的影响,探讨IGF-1对HIBD可能的保护作用及其机制.[方法] 新生C57/BL小鼠180只,随机分为正常对照组、HIBD组和HIBD+IGF-1组,每组60只.采用改良Rice方法制备新生小鼠HIBD模型,HIBD+IGF-1组在术后即刻予腹腔注射IGF-1(50
[Objectives] To investigate the effect of Notch2 and Notch3 on cell proliferation and apoptosis of two trophoblast cell lines, BeWo and JAR.