【摘 要】
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Objective: Platelets can regulate endothelial cell genes expression through their adhesion to the subendothelium in response to vascular injury.Recently it has been reported that some endothelial cell
【机 构】
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Drug Discovery Research Center, Sichuan Medical University, Luzhou, China
【出 处】
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第十五届中国中西医结合学会微循环专业委员会暨第二届中国微循环学会痰瘀专业委员会学术会议
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Objective: Platelets can regulate endothelial cell genes expression through their adhesion to the subendothelium in response to vascular injury.Recently it has been reported that some endothelial cells (ECs)-secreted genes can modulate vascular smooth muscle cells (VSMCs) phenotypic transformation by ECs/VSMCs co-culture.However, little is known about the effects of platelets adhesion to ECs interaction on VSMCs phenotype.In this study, we investigated the role of some genes secreted by platelets adhesion to EC in regulating SMC phenotypic transformation.
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