Thalidomide Combined With Radiotherapy for Esophageal Cancer: Results From a Phase Ⅱ Trial

来源 :第十七届全国临床肿瘤学大会暨2014年CSCO学术年会 | 被引量 : 0次 | 上传用户:mx520ht
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Objective: To observe the variation of serum vascular endothelial growth factor (VEGF), short-term efficacy and tolerability in esophageal cancer (EC) patients treated by radiotherapy plus thalidomide.Method: The serum samples of 86 EC patients were collected before, during and after radiotherapy, and the VEGF level was examined by ELISA.According to the change of serum VEGF level during radiotherapy,the patients were divided into two groups: in the drug group VEGF level was increased or remained unchanged, and thalidomide was administered till the end of radiotherapy;in the non-drug group VEGF level was decreased and radiotherapy was given alone to the end.Thirty healthy volunteer served as controls.
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