透明质酸寡糖多价物的合成

来源 :第二届糖合成化学青年学术研讨会 | 被引量 : 0次 | 上传用户:zqfc2058
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透明质酸是一种线性大分子糖胺聚糖,能够被特定的受体蛋白如CD44、RHAMM 等所识别,并直接或间接地介导细胞内信号传导,从而调控细胞的粘附、生长、分化和激活特异性细胞类型,调控免疫反应、血管化和愈合过程.许多疾病如癌症、炎症、心脏病、肾病等都与这一过程密切相关1.
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