[目的]探讨射波刀治疗鼻咽癌颅底复发和转移病灶的毒性与疗效.[方法]回顾性分析2006.10～2014.3射波刀治疗鼻咽癌调强放疗后颅底复发或转移的患者21例.射波刀治疗采用颅骨追踪方式,67％～83％剂量线,给予2400～5000cGy剂量,4～10次分割完成.通过影像学和症状随访进行毒性和疗效的评估.采用Kaplan-Meier方法进行局控疗效和总生存评估.[结果]1、2、3年局部无进展生存率
Background: Lung metastasis is one of the most important causes of death in patients with nasopharyngeal carcinoma (NPC).NPC with lung metastasis alone has been reported to show a relatively favorable
Background:Some articles reported that some breast cancer, NSCLC and etc patients with hypertension who received definitive radiotherapy and concurrently use the beta-blocker medicine had better survi
Background:The impact of combining plasma fibrinogen levels with Epstein-Barr Virus DNA(EBV DNA)levels on the prognosis for patients with nasopharyngeal carcinoma(NPC) was evaluated.Patients and Metho
Purpose:To report the incidence of mastoiditis and risk factors for nasopharyngeal carcinoma (NPC) patients receiving intensity-modulated radiotherapy(IMRT) ,and to recognize the effects of radiation
[目的]分析艾滋病期患者合并鼻咽癌的放射治疗并发症、疗效。[方法]收集我院2006年1月至2010年12月,经确诊并在有效职业暴露预防措施下,对行放射治疗的5例艾滋病期患者合并鼻咽癌的临床资料进行分析。患者男性4例,女性1例,年龄40～63岁,中位43岁；因涕血、鼻塞、耳鸣、头痛伴颈部淋巴结肿大3例,颈部淋巴结肿大2例,3例伴体重下降3 ～9kg就诊；既往有输血史1例,美容手术史1例,余患者流行学
[目的]观察Ⅲ～Ⅳb期的鼻咽癌采用时辰诱导化疗加同步放化疗与同步放化疗加辅助化疗的不良反应和近期疗效.[方法]将69例确诊的初治鼻咽癌患者,采用随机数字法分时辰诱导化疗加同步放化疗组(诱导化疗组)和同步放化疗加辅助化疗组(辅助化疗组).诱导化疗和辅助化疗采用TPF方案化疗3个周期(TPF： DOC 75mg/m2,静滴,d1；DDP： 75mg/m2,静脉泵入10am～10pm,d1～5,共60h
Objective:For nasopharyngeal carcinoma(NPC),the local control(LC) has been reached to more than 90% treated with radiotherapy.The most concern problem is distant metastasis which still remains high in
Objectives:To investigate the clinical characteristics and prognostic factors of post-irradiation tongue squamous cell carcinoma(PTSCC) after definitive radiation for nasopharyngeal carcinoma(NPC) and
目的 化合物DW10075为靶向设计合成的潜在VEGFR抑制剂，为新结构苯胺嘧啶萘酰胺类衍生物。本课题开展DW10075的靶点抑制活性、新生血管生成抑制活性和体内、外抗肿瘤活性检测，深入研究其抗肿瘤作用机制。方法 首先采用酶联免疫吸附试验(ELISA)，研究DW10075对多种酪氨酸激酶的抑制作用，确定其VEGFR激酶抑制活性及其选择性。然后，在人原代脐静脉内皮细胞(HUVEC)中，采用磺酰罗丹明