【摘 要】
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Turner syndrome (TS) is a heterogenous genetic disorder caused by X-chromosomal structural abnormalities that affects in about 1 of 2500 females.The affecte
【机 构】
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Institute of Pediatric Translational Medicine, Shanghai Children's Medical Center, Shanghai Jiaoton
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Turner syndrome (TS) is a heterogenous genetic disorder caused by X-chromosomal structural abnormalities that affects in about 1 of 2500 females.The affected individuals may develop diverse clinical features, including short stature, ovarian dysgenesis, skeletal dysplasia, facial abnormalities and other disorders.Karyotype of 45, X accounts for nearly 50% in Turner patients, other X-chromosomal structural abnormalities, containing deletions, duplications, rings, isodicentric chromosomes, inversions, and translocations have been reported, successively.
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