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Influenza A viral (IAV) fusion peptides are known for their important role in viral-cell fusion process and membrane destabilization potential which are compatible with those of antimicrobial peptides.Thus,we synthesized several potent antimicrobial peptides derived from the fusogenic peptides (FPs) of hemaglutinin glycoproteins (HAs) of IAV by replacing the negatively or neutrally charged residues of FPs with positively charged lysines.