Objective: Whether adjuvant chemoradiotherapy (ACRT) or chemotherapy (ACT) will benefit for stage Ⅱ or Ⅲ upper rectal cancer (URC) after radical surgery remains unclear.
Objective: Pancreatic cancer is currently one of the deadliest solid malignancies and pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer.
Objective: Gemcitabine (GEM) is a standard treatment in patients with advanced pancreatic cancer (PC).S-1 has shown a good efficacy and well safety in Japanese patients from previous studies and has b
Background: HCC, a poor-prognosis disease for which the only approved drug is sorafenib, has a high unmet need.Factors associated with tumor aggressiveness in advanced HCC include c-Met amplification/
Objective: Colorectal cancer (CRC) is one of the most common malignant tumors.Most of advanced CRC will progress after first-line treatment;therefore, seeking an efficient and low toxic maintaining re
Objective: To evaluate the potential utility of circulating tumor cells (CTCs) measurements in predicting prognosis of hepatocellular carcinoma (HCC) patients received trans arterial chemoembolization
Objective: Although it has been shown that polymorphisms in one-carbon metabolism (OCM) pathway are associated with gastric cancer (GC), their interactions and contributions for patients survival are
Objective: To avoid the damage of radiotherapy for rectal cancer patients, we have designed a phase Ⅱ study comparing Neoadjuvant mFOLFOX6 chemotherapy with or without radiation in locally advanced re
目的: The combination of nab-paclitaxel and cisplatin as preoperative treatment for esophageal squamous cell carcinoma (ESCC) has not been investigated.
目的:分析KRAS,NRAS,BRAF突变情况与结直肠癌患者的临床病理学特征,特别是转移的发生发展进程的关系。方法:序列分析法检测384例结直肠患者的KRAS外显子2,3,4,NRAS外显子2,3,4,BRAF外显子15的突变,并回顾性分析KRAS,NRAS,BRAF突变情况与临床病理学特点间的联系,探讨其与转移方式的关系。