Mitoguardin, a novel mitochondrial protein, regulates mitochondria dynamics and neuronal homeostasis

来源 :中国细胞生物学学会2015年全国学术大会 | 被引量 : 0次 | 上传用户：lkks06

【摘要】

：

　　Mitochondria undergo frequent morphologic changes through fission and fusion.Mutations in several core mitochondial fission /fusion machinery cause severe n

【作者】

：

Yongping Zhang Xiaoman Liu Jian Bai Xuejun Tian Jianjie Zhou Huan Yang Chao Tong

【机构】

：

LifeSciencesInstituteandInnovationCenterforCellBiology,ZhejiangUniversity,Hangzhou310058,China

【出处】

：

中国细胞生物学学会2015年全国学术大会

【发表日期】

：

2015年4期

【关键词】

：

Mitochondrial fusion Neurodegeneration Drosophila

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　　Mitochondria undergo frequent morphologic changes through fission and fusion.Mutations in several core mitochondial fission /fusion machinery cause severe neurodegenerative diseases, such as Charcot-Marie-Tooth subtype 2A and autosomal dominant optic atrophy.

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Mitoguardin, a novel mitochondrial protein, regulates mitochondria dynamics and neuronal homeostasis

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